Product Name: C10orf2 Antibody
Species Reactivity: Human
Tested Applications: IHC-P, WB
Applications: For WB starting dilution is: 1:1000For IHC-P starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 77 kDa
Immunogen: This C10orf2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 656-684 amino acids from the C-terminal region of human C10orf2.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 1084-65-7
Product: Meticrane
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.38 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Twinkle protein, mitochondrial, Progressive external ophthalmoplegia 1 protein, T7 gp4-like protein with intramitochondrial nucleoid localization, T7-like mitochondrial DNA helicase, PEO1, C10orf2
Accession NO.: Q96RR1
Protein Ino: 74752111
Official Symbol: PEO1
Geneid: 56652
Background: This gene encodes a hexameric DNA helicase which unwindsshort stretches of double-stranded DNA in the 5 to 3 directionand, along with mitochondrial single-stranded DNA binding proteinand mtDNA polymerase gamma, is thought to play a key role in mtDNAreplication. The protein localizes to the mitochondrial matrix andmitochondrial nucleoids. Mutations in this gene cause infantileonset spinocerebellar ataxia (IOSCA) and progressive externalophthalmoplegia (PEO) and are also associated with severalmitochondrial depletion syndromes. Alternative splicing results inmultiple transcript variants encoding distinct isoforms.
PubMed ID:http://aac.asm.org/content/42/7/1745.abstract
