Product Name: ANKLE1 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Applications: ANKLE1 antibody can be used for detection of ANKLE1 by Western blot at 1 – 2 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: ANKLE1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human ANKLE1.The immunogen is located within the last 50 amino acids of ANKLE1.
Host Species: Chicken
Purification: ANKLE1 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 1382979-44-3
Product: GDC-0084
Buffer: ANKLE1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: ANKLE1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: ANKLE1 Antibody: LEM3, LEMD6, ANKRD41, LEM3, Ankyrin repeat and LEM domain-containing protein 1, Ankyrin repeat domain-containing protein 41
Accession NO.: NP_689576
Protein Ino: 168229256
Official Symbol: ANKLE1
Geneid: 126549
Background: ANKLE1 Antibody: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. ANKLE1 (Ankyrin repeat and LEM domain containing 1) is a member of ankyrin repeat and LEM domain containing family. It is a potential single-pass membrane protein that contains ankyrin repeats and a Lem domain. Ankyrin repeats mediate protein-protein interactions and are among the most common structural motifs in known proteins. While the function of this protein is still under investigation, its gene locus has been associated with susceptibility to ovarian and breast cancer.
PubMed ID:http://aac.asm.org/content/52/11/4121.abstract
