Product Name: ANGPTL7 Antibody [Kairos 108-4]
Species Reactivity: Human
Tested Applications: ELISA, IHC, WB
Applications: ELISA: (direct or indirect: 1:2,000-1:5,000). Immunohistochemistry: (paraffin sections (1:100)). Western blot: (1:2,000-1:5,000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature). Optimal conditions should be determined individually for each application.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Recombinant human full length ANGPTL7.
Host Species: Mouse
Purification:
Physical State: Liquid
CAS NO.: 374913-63-0
Product: Madrasin
Buffer: Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration: 1 mg/ml
Storage Conditions: Stable for at least 1 year after receipt when stored at -20˚C.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: Angiopoietin-like Protein 7; Cornea-derived Transcript 6 Protein
Accession NO.: O43827
Protein Ino: 62899821
Official Symbol: ANGPTL7
Geneid: 10218
Background: ANGPTL7 is expressed in various tissues and regulates angiogenesis. Human ANGPTL7 was characterized as a potent target gene of the WNT/ beta-catenin signaling pathway, and is a pharmacogenomics target in the fields of oncology and regenerative medicine. Overexpression of ANGPTL7 increases collagen expression and might exert a pathogenic role in glaucoma.
PubMed ID:http://aac.asm.org/content/52/11/3928.abstract