Product Name: EphA10 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Applications: EphA10 antibody can be used for detection of EphA10 by Western blot at 1 – 2 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: EphA10 antibody was raised against a 14 amino acid synthetic peptide of near the amino terminus of human EphA10.The immunogen is located within amino acids 120 – 170 of EphA10.
Host Species: Rabbit
Purification: EphA10 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 404950-80-7
Product: Panobinostat
Buffer: EphA10 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: EphA10 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: EphA10 Antibody: Ephrin type-A receptor 10
Accession NO.: NP_001092909
Protein Ino: 150456460
Official Symbol: EPHA10
Geneid: 284656
Background: EphA10 Antibody: Eph receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility of neuronal and endothelial cells in central nervous system function and in development. Eph receptors can be divided into two subgroups: EphA and EphB. In mammals, the EphA class consists of eight members (EphA 1-7 and 10) that in general bind to ephrin-A members linked to the cell membrane through a glycosylphosphatidylinositol linkage. The EphB class consists of six members (EphB 1-6) that in general bind ephrin-B members that transverse the cell membrane. The Ephrin / EPH signaling pathway networks with the WNT signaling pathway during embryogenesis, tissue regeneration, and carcinogenesis. Recent studies show that Eph/EFN might be relevant in normal B-cell biology and could represent new potential prognostic markers and therapeutic targets for CLL.
PubMed ID:http://aac.asm.org/content/39/12/2752.abstract
