Product Name: Early Growth Response 1 Antibody
Species Reactivity: Chimpanzee, Human, Mouse
Tested Applications: ELISA, IHC, WB
Applications: Early Growth Response 1 antibody can be used in ELISA, Western Blot starting at 2 – 4 μg/mL, immunohistochemistry starting at 5 μg/mL, and immunofluorescence.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Early Growth Response 1 antibody was raised against amino acids 94 – 108 of Early Growth Response 1 (Human).
Host Species: Rabbit
Purification: Immunoaffinity Chromatography
Physical State: Liquid
CAS NO.: 1245537-68-1
Product: NVP-BGT226
Buffer: 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
Concentration:
Storage Conditions: Store Early Growth Response 1 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: EGR1, AT225, Early growth response 1, G0S30, KROX24, NGFIA, KROX-24, TIS8, ZIF-268, ZIF268, Zinc finger protein Krox-24, EGR-1, NGFI-A, Transcription factor ETR103, Transcription factor Zif268, Zinc finger protein 225
Accession NO.: P18146
Protein Ino: 119242
Official Symbol: EGR1
Geneid: 1958
Background: EGR-1 (also called Early Growth Response protein 1, Krox-24 protein, ZIF268, Nerve growth factor-induced protein A or NGFI-A, Transcription factor ETR103, and Zinc finger protein 225 or AT225) is a transcriptional regulator that recognizes and binds to the DNA sequence 5-CGCCCCCGC-3 (EGR-site). EGR-1 activates the transcription of target genes whose products are required for mitogenesis and differentiation. EGR-1 is a nuclear protein induced by growth factors. Expression has been identified in a variety of cancers.
PubMed ID:http://aac.asm.org/content/39/3/760.abstract