Product Name: EPM2A Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, ICC, IF, WB
Applications: EPM2A antibody can be used for detection of EPM2A by Western blot at 1 – 2 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 36 kDa
Immunogen: EPM2A antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human EPM2A.The immunogen is located within amino acids 190 – 240 of EPM2A.
Host Species: Rabbit
Purification: EPM2A Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 345627-80-7
Product: SNS-032
Buffer: EPM2A Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: EPM2A antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: EPM2A Antibody: EPM2, MELF, Laforin, Lafora PTPase, LAFPTPase
Accession NO.: NP_005661
Protein Ino: 11321613
Official Symbol: EPM2A
Geneid: 7957
Background: EPM2A Antibody: The Epilepsy, progressive myoclonus type 2A protein (EPM2A) is a dual-specificity phosphatase that associates with polyribosomes. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. EPM2A interacts with a number of proteins known to be involved in glycogen metabolism and has been shown to have robust phosphatase activity against a phosphorylated complex carbohydrate, suggesting that EPM2A may be involved in the regulation of glycogen metabolism.
PubMed ID:http://aac.asm.org/content/40/1/75.abstract
