Product Name: EPHA4 Antibody
Species Reactivity: Bat, Bovine, Dog, Gibbon, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Tested Applications: ELISA, IHC
Applications: EPHA4 antibody can be used in immunohistochemistry starting at 7.3 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: EPHA4 antibody was raised against a peptide located in the C-Terminal domain of EPHA4 (Human).
Host Species: Rabbit
Purification: Immunoaffinity Chromatography
Physical State: Liquid
CAS NO.: 141430-65-1
Product: ABT-751
Buffer: PBS, 0.1% sodium azide.
Concentration:
Storage Conditions: EPHA4 antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: EPHA4, CEK8, EK8, Ephrin type-A receptor 4, HEK8, SEK, TYRO1, TYRO1 protein tyrosine kinase, Tyrosine-protein kinase TYRO1, EPH receptor A4, EPH-like kinase 8
Accession NO.: P54764
Protein Ino: 1711371
Official Symbol: EPHA4
Geneid: 2043
Background: Nak1, a NR4 Nerve Growth Factor-Like receptor, has been shown to affect the hypothalamic-pituitary axis, neuronal differentiation, neuroendocrine regulation of adrenocortical function, and T-cell apoptosis. Nak1 also is known as nuclear receptor Tr3 and is similar to mouse Nur77 and rat NGFI-B. It is encoded by one of the immediate early genes (IEG) in response to nerve growth factor and other serum growth factors. Nak1 can bind to DNA as a monomer, homodimer, or heterodimer (with retinoid X receptors). Nak1 has been shown to inhibit vascular lesion formation and could serve as a novel target in the treatment of vascular diseases.
PubMed ID:http://aac.asm.org/content/39/12/2792.abstract
