Product Name: ENG Antibody
Species Reactivity: Human
Tested Applications: ELISA, IHC, WB
Applications: ENG antibody can be used for detection of ENG by ELISA at 1:312500. ENG antibody can be used for detection of ENG by western blot at 2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 68 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ENG.
Host Species: Rabbit
Purification: Antibody is purified by protein A chromatography method.
Physical State: Lyophilized
CAS NO.: 586379-66-0
Product: PH-797804
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store ENG antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: ENG, END, HHT1, ORW1
Accession NO.: NP_000109
Protein Ino: 4557555
Official Symbol: ENG
Geneid: 2022
Background: Endoglin is a homodimeric transmembrane glycoprotein highly expressed by endothelial cells. It is a component of the transforming growth factor beta receptor complex since it binds TGFB1 and TGFB3 with high affinity. Mutations in the endoglin gene produce hereditary hemorrhagic telangiectasia.
PubMed ID:http://aac.asm.org/content/39/10/2304.abstract
