Product Name: ELAVL3 Antibody
Species Reactivity: Human
Tested Applications: IHC-P, WB
Applications: For WB starting dilution is: 1:1000For IHC-P starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 40 kDa
Immunogen: This ELAVL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-99 amino acids from the N-terminal region of human ELAVL3.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 1109276-89-2
Product: PF-04620110
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: ELAV-like protein 3, Hu-antigen C, HuC, Paraneoplastic cerebellar degeneration-associated antigen, Paraneoplastic limbic encephalitis antigen 21, ELAVL3, HUC, PLE21
Accession NO.: Q14576
Protein Ino: 21264436
Official Symbol: ELAVL3
Geneid: 1995
Background: A member of the ELAVL protein family, ELAV-like 3 is aneural-specific RNA-binding protein which contains three RNP-typeRNA recognition motifs. The observation that ELAVL3 is one ofseveral Hu antigens (neuronal-specific RNA-binding proteins)recognized by the anti-Hu serum antibody present in sera frompatients with paraneoplastic encephalomyelitis and sensoryneuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Twoalternatively spliced transcript variants encoding distinctisoforms have been found for this gene.
PubMed ID:http://aac.asm.org/content/39/8/1871.abstract
