Product Name: EDEM3 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 105 kDa
Immunogen: This EDEM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 774-802 amino acids from the C-terminal region of human EDEM3.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 957054-30-7
Product: GDC-0941
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.43 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: ER degradation-enhancing alpha-mannosidase-like protein 3, Alpha-1,2-mannosidase EDEM3, EDEM3, C1orf22
Accession NO.: Q9BZQ6
Protein Ino: 166897965
Official Symbol: EDEM3
Geneid: 80267
Background: Quality control in the endoplasmic reticulum (ER) ensuresthat only properly folded proteins are retained in the cell throughrecognition and degradation of misfolded or unassembled proteins.EDEM3 belongs to a group of proteins that accelerate degradation ofmisfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed16431915]).
PubMed ID:http://aac.asm.org/content/39/4/996.abstract
