Product Name: EDA1 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IF, IHC-P, WB
Applications: EDA1 antibody can be used for detection of EDA1 by Western blot at 1 – 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 16, 43 kDa Observed: 39 kDa
Immunogen: EDA1 antibody was raised against an 19 amino acid peptide near the center of human EDA1.The immunogen is located within amino acids 130 – 180 of EDA1.
Host Species: Rabbit
Purification: EDA1 antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 1173900-33-8
Product: AZD 6482
Buffer: EDA1 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: EDA1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Ectodysplasin A, Ectodermal dysplasia protein, ED1, ED1-A1, ED1-A2, EDA1, EDA2, EDA protein, HED, ODT1, STHAGX1, XHED, XLHED
Accession NO.: NP_001390
Protein Ino: 4503449
Official Symbol: EDA
Geneid: 1896
Background: Ectodysplasin A (EDA1) is a member of the TNF-related ligand family involved in the early epithelial-mesenchymal interaction that regulates ectodermal appendage formation (1). It is a trimeric type II membrane protein that co-localizes with cytoskeletal structures at the lateral and apical surfaces of cells and can be expressed as eight alternatively spliced isoforms in hair follicles and in the epidermis of adult skin (2,3). EDAs are required during development, and loss or mutation of EDA1 results in a group of developmental disorders identified as ectodermal dysplasia type 1 (4,5).
PubMed ID:http://aac.asm.org/content/39/4/979.abstract
