Product Name: DSC1 Antibody
Species Reactivity: Human
Tested Applications: Flow, IHC-P, WB
Applications: For WB starting dilution is: 1:1000For FACS starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 100 kDa
Immunogen: This DSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 659-687 amino acids from the C-terminal region of human DSC1.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 1217448-46-8
Product: VD2-D3
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Desmocollin-1, Cadherin family member 1, Desmosomal glycoprotein 2/3, DG2/DG3, DSC1, CDHF1
Accession NO.: Q08554
Protein Ino: 223590198
Official Symbol: DSC1
Geneid: 1823
Background: DSC1 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined.
PubMed ID:http://aac.asm.org/content/39/1/56.abstract
