Product Name: DOCK8 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IHC-P, WB
Applications: DOCK8 antibody can be used for detection of DOCK8 by Western blot at 1 – 2 μg/ml. Antibody can also be used for Immunohistochemistry at 5 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 166, 220, 231 kDa Observed: 220, 230 kDa
Immunogen: DOCK8 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human DOCK8.The immunogen is located within the last 50 amino acids of DOCK8.
Host Species: Rabbit
Purification: DOCK8 antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 1058137-23-7
Product: E-3810
Buffer: DOCK8 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: DOCK8 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: DOCK8 Antibody: MRD2, ZIR8, HEL-205, Dedicator of cytokinesis protein 8
Accession NO.: NP_982272
Protein Ino: 238231392
Official Symbol: DOCK8
Geneid: 81704
Background: The Dedicator of cytokinesis protein 8 (DOCK8) is a member of the DOCK180 family of guanine nucleotide exchange factors (1). DOCK8 plays an essential role in humoral immune responses and is important in the proper formation of the B cell immunological synapse (reviewed in 2). Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome (3).
PubMed ID:http://aac.asm.org/content/38/11/2553.abstract
