Product Name: DNM1L Antibody
Species Reactivity: Human, Mouse
Tested Applications: ELISA, ICC, IF, WB
Applications: DNM1L antibody can be used for detection of DNM1L by Western blot at 1 – 2 μg/ml. Antibody can also be used for Immunocytochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 81 kDa Observed: 80 kDa
Immunogen: DNM1L antibody was raised against a 19 amino acid peptide near the center of human DNM1L.The immunogen is located within amino acids 530 – 580 of DNM1L.
Host Species: Rabbit
Purification: DNM1L antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 1672-88-4
Product: Furagin
Buffer: DNM1L antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: DNM1L antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: DNM1L Antibody: DLP1, DRP1, DVLP, EMPF, DYMPLE, HDYNIV, DLP1, Dynamin-1-like protein, Dynamin family member proline-rich carboxyl-terminal domain less
Accession NO.: NP_036192
Protein Ino: 171460914
Official Symbol: DNM1L
Geneid: 10059
Background: The Dynamin-1-like protein (DNM1L) is a member of the dynamin superfamily of GTPases (1). DNM1L mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis (2). Dysfunction of this gene is implicated in several neurological disorders, including Alzheimers disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF) (3).
PubMed ID:http://aac.asm.org/content/38/10/2471.abstract
