Product Name: DNA PKcs (Ab 2609) Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: Western Blot: 1:500~1:1000
User Note:
Predicted Molecular Weight: 450 kDa
Immunogen: DNA PKcs (Ab-2609) antibody was raised against a peptide sequence around aa.2607~2611 (V-E-T-Q-A) derived from Human DNA-PK.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Physical State: Liquid
CAS NO.: 869113-09-7
Product: Umeclidinium (bromide)
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: HYRC, p350, DNAPK, DNPK1, HYRC1, XRCC7, DNA-PKcs, EPLG5, HTKL, LERK5, PRKD, PRKDC, P460
Accession NO.: NP_001075109.1
Protein Ino: 126032350
Official Symbol: PRKDC
Geneid: 5591
Background: The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties
PubMed ID:http://aac.asm.org/content/38/9/2204.abstract
