Product Name: DMGDH Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 97 kDa
Immunogen: This DMGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 836-864 amino acids from the C-terminal region of human DMGDH.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 104632-25-9
Product: Pramipexole (dihydrochloride)
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Dimethylglycine dehydrogenase, mitochondrial, ME2GLYDH, DMGDH
Accession NO.: Q9UI17
Protein Ino: 296434575
Official Symbol: DMGDH
Geneid: 29958
Background: This gene encodes an enzyme involved in the catabolism ofcholine, catalyzing the oxidative demethylation of dimethylglycineto form sarcosine. The enzyme is found as a monomer in themitochondrial matrix, and uses flavin adenine dinucleotide andfolate as cofactors. Mutation in this gene causes dimethylglycinedehydrogenase deficiency, characterized by a fishlike body odor,chronic muscle fatigue, and elevated levels of the muscle form ofcreatine kinase in serum.
PubMed ID:http://aac.asm.org/content/38/9/2143.abstract
