Product Name: DMAP1 Antibody
Species Reactivity: Dog, Human, Mouse
Tested Applications: ELISA, WB
Applications: DMAP1 antibody can be used for detection of DMAP1 by ELISA at 1:62500. DMAP1 antibody can be used for detection of DMAP1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 51 kDa, 53 kDa, 53 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DMAP1.
Host Species: Rabbit
Purification: Antibody is purified by protein A chromatography method.
Physical State: Lyophilized
CAS NO.: 49562-28-9
Product: Fenofibrate
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store DMAP1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: DMAP1, EAF2, SWC4, MEAF2, DNMAP1, DNMTAP1
Accession NO.: NP_001029196
Protein Ino: 78000213
Official Symbol: DMAP1
Geneid: 55929
Background: DMAP1 is a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.
PubMed ID:http://aac.asm.org/content/38/9/2125.abstract
