Product Name: DLC1 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Applications: DLC1 antibody can be used for detection of DLC1 by ELISA at 1:12500. DLC1 antibody can be used for detection of DLC1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 52 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DLC1.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 159989-65-8
Product: Nelfinavir (Mesylate)
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store DLC1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: DLC1, ARHGAP7, FLJ21120, HP, STARD12, p122-RhoGAP
Accession NO.: EAW63852
Protein Ino: 119584256
Official Symbol: DLC1
Geneid: 10395
Background: This gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers. DLC1 functions as a GTPase-activating protein specific for Rho and an activator of PLCD1 in vivo and induces morphological changes and detachment through cytoskeletal reorganization.
PubMed ID:http://aac.asm.org/content/38/9/1915.abstract
