Product Name: DIABLO Antibody
Species Reactivity: Human
Tested Applications: ELISA, WB
Applications: DIABLO antibody can be used for detection of DIABLO by ELISA at 1:312500. DIABLO antibody can be used for detection of DIABLO by western blot at 0.3125 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 21 kDa, 27 kDa, 22 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DIABLO.
Host Species: Rabbit
Purification: Antibody is purified by protein A chromatography method.
Physical State: Lyophilized
CAS NO.: 35943-35-2
Product: Triciribine
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store DIABLO antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: DIABLO, SMAC, DFNA64
Accession NO.: NP_620308
Protein Ino: 21070978
Official Symbol: DIABLO
Geneid: 56616
Background: DIABLO is an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Several alternatively spliced transcript variants that encode distinct isoforms have been described for this gene but the validity of some transcripts, and their predicted ORFs, has not been determined conclusively.
PubMed ID:http://aac.asm.org/content/38/7/1661.abstract
