Product Name: DCNP1 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IF, IHC-P, WB
Applications: DCNP1 antibody can be used for detection of DCNP1 by Western blot at 1 – 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 27 kDa Observed: 24 kDa
Immunogen: DCNP1 antibody was raised against an 18 amino acid peptide near the amino terminus of human DCNP1.The immunogen is located within the first 50 amino acids of DCNP1.
Host Species: Rabbit
Purification: DCNP1 antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 1071638-38-4
Product: MAC13243
Buffer: DCNP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: DCNP1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: DCNP1 Antibody: DCNP1, C5orf20, Dendritic cell nuclear protein 1
Accession NO.: NP_570900
Protein Ino: 18677770
Official Symbol: C5orf20
Geneid: 140947
Background: The DCNP1 (dendritic cell nuclear protein 1) gene is specifically expressed in dendritic cells, potent antigen-presenting cells involved in activating naive T cells to initiate antigen-specific immune response (1). It is localized mainly in the perinucleus. One of the alleles (A/T) of this gene causes premature translation termination at aa 117 and has been associated with an increased prevalence of major depression in humans (2,3). DCNP1 may play a role in the pathogenesis of depressive disorders by enhancing corticotropin-releasing hormone expression in the hypothalamic paraventricular nucleus (4).
PubMed ID:http://aac.asm.org/content/38/4/668.abstract
