Product Name: DAP Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IF, IHC-P, WB
Applications: DAP antibody can be used for detection of DAP by Western blot at 1 – 2 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 11 kDa Observed: 11 kDa
Immunogen: DAP antibody was raised against a 19 amino acid peptide near the carboxy terminus of human DAP.The immunogen is located within the last 50 amino acids of DAP.
Host Species: Rabbit
Purification: DAP Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 874819-74-6
Product: Toceranib (phosphate)
Buffer: DAP Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: DAP antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: DAP Antibody: DAP1, Death-associated protein 1, DAP-1
Accession NO.: NP_004385
Protein Ino: 4758120
Official Symbol: DAP
Geneid: 1611
Background: DAP Antibody: The Death-associated protein (DAP) is a basic proline-rich 15kDa protein that as a positive mediator of programmed cell death that is induced by interferon-gamma (1). DAP is also a direct substrate of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Under rich nutrient conditions, mTOR phosphorylates DAP at Ser3 and Ser51; under starvation conditions, these residues are dephosphorylated and DAP is converted into an active suppressor of autophagy (2).
PubMed ID:http://aac.asm.org/content/38/2/353.abstract
