Product Name: DAF Antibody
Species Reactivity: Human
Tested Applications: ELISA, IF, IHC-P, WB
Applications: DAF body can be used for detection of DAF by Western blot at 1 – 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 48 kDa Observed: 49 kDa
Immunogen: DAF antibody was raised against an 18 amino acid peptide near the carboxy terminus of human DAF.The immunogen is located within amino acids 360 – 410 of DAF.
Host Species: Rabbit
Purification: DAF antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 137234-62-9
Product: Voriconazole
Buffer: DAF antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: DAF antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Decay-accelerating factor, CD55 molecule decay accelerating factor for complement (Cromer blood group), CD55, CR, TC, CROM
Accession NO.: NP_001108224
Protein Ino: 168693643
Official Symbol: CD55
Geneid: 1604
Background: The decay-accelerating factor (DAF), also known as CD55, is an integral membrane glycoprotein that is involved in the regulation of the complement cascade (1). DAF limits excessive complement activation by accelerating their decay following DAF binding, thereby disrupting the cascade and preventing damage to host cells (2). Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM) (3).
PubMed ID:http://aac.asm.org/content/38/2/326.abstract
