Product Name: DAAM1-T361 Antibody
Species Reactivity: Hamster, Human
Tested Applications: Flow, IHC-P, WB
Applications: For WB starting dilution is: 1:1000For IHC-P starting dilution is: 1:50~100For FACS starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 123 kDa
Immunogen: This DAAM1-T361 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the N-terminal region of human DAAM1-T361.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 1431698-10-0
Product: OTSSP167 (hydrochloride)
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Disheveled-associated activator of morphogenesis 1, DAAM1, KIAA0666
Accession NO.: Q9Y4D1
Protein Ino: 34098767
Official Symbol: DAAM1
Geneid: 23002
Background: Functions of the cell cortex, including motility,adhesion, and cytokinesis, are mediated by the reorganization ofthe actin cytoskeleton and recent evidence suggests a role for theFormin homology (FH) proteins in these processes. The proteinencoded by this gene contains FH domains and belongs to a novel FHprotein subfamily implicated in cell polarity. Wnt/Fz signalingactivates the small GTPase Rho, a key regulator of cytoskeletonarchitecture, to control cell polarity and movement duringdevelopment. Activation requires Dvl-Rho complex formation, anassembly mediated by this gene product, which is thought tofunction as a scaffolding protein. Evidence of alternative splicinghas been observed for this gene but the full-length nature of thesevariants has not been determined.
PubMed ID:http://aac.asm.org/content/38/2/260.abstract
