Product Name: Chondroadherin Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, ICC, WB
Applications: Chondroadherin antibody can be used for detection of Chondroadherin by Western blot at 1 – 2 μg/ml. Antibody can also be used for immunocytochemistry starting at 5 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 38 kDa Observed: 36 kDa
Immunogen: Chondroadherin antibody was raised against a 17 amino acid peptide near the carboxy terminus of human Chondroadherin.The immunogen is located within the last 50 amino acids of Chondroadherin.
Host Species: Rabbit
Purification: Chondroadherin antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 1033805-22-9
Product: LX1606
Buffer: Chondroadherin antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: Chondroadherin antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Cartilage leucine-rich protein, CHAD, SLRR4A
Accession NO.: NP_001258
Protein Ino: 153251229
Official Symbol: CHAD
Geneid: 1101
Background: Chondroadherin, also known as CHAD or SLRR4A, belongs to the small leucine-rich proteoglycan (SLRP) family and class IV subfamily and plays a significant role in the regulation of chondrocyte growth and proliferation (1,2). It localizes to the extracellular matrix and contains nine tandem leucine repeats as well as N-terminal and C-terminal leucine rich domains (2-4). Chondroadherin is implicated in the adhesion of fibroblasts, osteoblasts and chondrocytes, which is mediated by interactions with Integrin alpha2 beta1 (2,4,5).
PubMed ID:http://aac.asm.org/content/36/2/308.abstract
