Product Name: CaMK4 (phospho Thr196/200) Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB
Applications: Western Blot: 1:500~1:1000
User Note:
Predicted Molecular Weight: 60 kDa
Immunogen: CaMK4 (phospho Thr196/200) antibody was raised against a peptide sequence around phosphorylation site of threonine 200 (M-K-T (p)-V-C) derived from Human CaMK4 or threonine 196 (M-K-T (p)-V-C) derived from Mouse CaMK4.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Physical State: Liquid
CAS NO.: 1313725-88-0
Product: Savolitinib
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CAM kinase-GR, CAMK4, CaMK IV, Calspermin, KCC4
Accession NO.: NP_001735.1
Protein Ino: 2499586
Official Symbol: CAMK4
Geneid: 814
Background: Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK4 signaling cascade and regulates, mainly by phosphorylation, the activity of several transcription activators, such as CREB1, MEF2D, JUN and RORA, which play pivotal roles in immune response, inflammation, and memory consolidation. In the thymus, regulates the CD4+/CD8+ double positive thymocytes selection threshold during T-cell ontogeny. In CD4 memory T-cells, is required to link T-cell antigen receptor (TCR) signaling to the production of IL2, IFNG and IL4 (through the regulation of CREB and MEF2).
PubMed ID:http://aac.asm.org/content/43/3/543.abstract
