Product Name: CYTH1 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 46 kDa
Immunogen: This CYTH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human CYTH1.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 143-67-9
Product: Vinblastine (sulfate)
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Cytohesin-1, PH, SEC7 and coiled-coil domain-containing protein 1, SEC7 homolog B2-1, CYTH1, D17S811E, PSCD1
Accession NO.: Q15438
Protein Ino: 2498175
Official Symbol: CYTH1
Geneid: 9267
Background: The protein encoded by this gene is a member of the PSCDfamily. Members of this family have identical structuralorganization that consists of an N-terminal coiled-coil motif, acentral Sec7 domain, and a C-terminal pleckstrin homology (PH)domain. The coiled-coil motif is involved in homodimerization, theSec7 domain contains guanine-nucleotide exchange protein (GEP)activity, and the PH domain interacts with phospholipids and isresponsible for association of PSCDs with membranes. Members ofthis family appear to mediate the regulation of protein sorting andmembrane trafficking. This gene is highly expressed in naturalkiller and peripheral T cells, and regulates the adhesiveness ofintegrins at the plasma membrane of lymphocytes. The encodedprotein is 83% homologous to that of CYTH2.
PubMed ID:http://aac.asm.org/content/37/11/2496.abstract
