Product Name: CYSLTR1 Antibody
Species Reactivity: Human
Tested Applications: IHC-P, WB
Applications: For WB starting dilution is: 1:1000For IHC-P starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 39 kDa
Immunogen: This CYSLTR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-172 amino acids from the Central region of human CYSLTR1.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 23491-52-3
Product: Hoechst 33342
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Cysteinyl leukotriene receptor 1, CysLTR1, Cysteinyl leukotriene D4 receptor, LTD4 receptor, G-protein coupled receptor HG55, HMTMF81, CYSLTR1, CYSLT1
Accession NO.: Q9Y271
Protein Ino: 20138087
Official Symbol: CYSLTR1
Geneid: 10800
Background: The cysteinyl leukotrienes LTC4, LTD4, and LTE4 areimportant mediators of human bronchial asthma. Pharmacologicstudies have determined that cysteinyl leukotrienes activate atleast 2 receptors, the protein encoded by this gene and CYSLTR2.This encoded receptor is a member of the superfamily of Gprotein-coupled receptors. Activation of this receptor by LTD4results in contraction and proliferation of smooth muscle, oedema,eosinophil migration and damage to the mucus layer in the lung.
PubMed ID:http://aac.asm.org/content/37/11/2474.abstract
