Product Name: CYP5A1 Antibody
Species Reactivity: Mouse
Tested Applications: IHC-P, WB
Applications: For WB starting dilution is: 1:1000For IHC-P starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 61 kDa
Immunogen: This CYP5A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-257 amino acids from the Central region of human CYP5A1.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 23623-06-5
Product: HOE 32021
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.3 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Thromboxane-A synthase, TXA synthase, TXS, Cytochrome P450 5A1, TBXAS1, CYP5, CYP5A1
Accession NO.: P24557
Protein Ino:
Official Symbol: TBXAS1
Geneid: 6916
Background: This gene encodes a member of the cytochrome P450superfamily of enzymes. The cytochrome P450 proteins aremonooxygenases which catalyze many reactions involved in drugmetabolism and synthesis of cholesterol, steroids and other lipids.However, this protein is considered a member of the cytochrome P450superfamily on the basis of sequence similarity rather thanfunctional similarity. This endoplasmic reticulum membrane proteincatalyzes the conversion of prostglandin H2 to thromboxane A2, apotent vasoconstrictor and inducer of platelet aggregation. Theenzyme plays a role in several pathophysiological processesincluding hemostasis, cardiovascular disease, and stroke.Alternatively spliced transcript variants encoding differentisoforms have been found for this gene.
PubMed ID:http://aac.asm.org/content/37/11/2443.abstract
