Product Name: CXCR4 Antibody [12G5]
Species Reactivity: Baboon, Chimpanzee, Human, Monkey
Tested Applications: Flow, IF, IHC
Applications: CXCR4 antibody can be used in immunohistochemistry starting at 10 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen:
Host Species: Mouse
Purification: Affinity Chromatography
Physical State: Liquid
CAS NO.: 487021-52-3
Product: AR-A014418
Buffer: PBS, pH 7.2, 0.09% sodium azide. Sourced from tissue culture supernatant.
Concentration:
Storage Conditions: Store CXCR4 antibody at 4 ˚C, Avoid Freezing
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: CXCR4, CD184, CD184 antigen, Cmkar4, Cxc chemokine receptor 4, CXCR-4, CXC-R4, D2S201E, FB22, Fusin, HM89, LCR1, NPY3R, NPYRL, NPYY3R, Npyy3, HSY3RR, SDF-1 receptor, WHIM, C-x-c chemokine receptor 4, LESTR, Neuropeptide Y receptor Y3, NPYR
Accession NO.: P61073
Protein Ino: 46577576
Official Symbol: CXCR4
Geneid: 7852
Background: CXCR4, a Chemokine Receptor involved in organ vascularization, neuronal cell migration, and patterning of the central nervous system during development. It binds stromal cell-derived factor 1 (SDF1, also called PBFS) and mediates migration of resting leukocytes and is unique in homing hematopoietic progenitors to bone marrow. These properties suggest that CXCR4 is involved in tumor cell migration and local tumor invasion. It is also an HIV-1 fusion co-factor that allows HIV-1 invasion in diverse human cell types. Although this receptor was initially called Neuropeptide Y3 Receptor, it does not respond to neuropeptide Y. CXCR4 has two isoforms that are produced by alternative splicing.
PubMed ID:http://aac.asm.org/content/37/9/1842.abstract
