Product Name: CXCL12 Antibody
Species Reactivity: Human
Tested Applications: ELISA, WB
Applications: CXCL12 antibody can be used for detection of CXCL12 by ELISA at 1:62500. CXCL12 antibody can be used for detection of CXCL12 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 11 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CXCL12.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 1370261-97-4
Product: PRT062607 (Hydrochloride)
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store CXCL12 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CXCL12, IRH, PBSF, SDF1, TLSF, TPAR1, SCYB12
Accession NO.: NP_000600
Protein Ino: 10834988
Official Symbol: CXCL12
Geneid: 6387
Background: Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL1. The intercrines are characterized by the presence of 4 conserved cysteines which form 2 disulfide bonds. They can be classified into 2 subfamilies. In the CC subfamily, which includes beta chemokine, the cysteine residues are adjacent to each other. In the CXC subfamily, which includes alpha chemokine, they are separated by an intervening amino acid. The SDF1 proteins belong to the latter group.
PubMed ID:http://aac.asm.org/content/37/9/1749.abstract
