Product Name: CUL4B Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 104 kDa
Immunogen: This CUL4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-278 amino acids from the Central region of human CUL4B.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 104987-12-4
Product: Ascomycin
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Cullin-4B, CUL-4B, CUL4B, KIAA0695
Accession NO.: Q13620
Protein Ino: 296439468
Official Symbol: CUL4B
Geneid: 8450
Background: This gene is a member of the cullin family. The encodedprotein forms a complex that functions as an E3 ubiquitin ligaseand catalyzes the polyubiquitination of specific protein substratesin the cell. The protein interacts with a ring finger protein, andis required for the proteolysis of several regulators of DNAreplication including chromatin licensing and DNA replicationfactor 1 and cyclin E. Multiple transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
PubMed ID:http://aac.asm.org/content/37/8/1620.abstract
