Product Name: CTSK Antibody
Species Reactivity: Human
Tested Applications: IHC-P, WB
Applications: For WB starting dilution is: 1:1000For IHC-P starting dilution is: 1:10~50For FACS starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 37 kDa
Immunogen: This CTSK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-126 amino acids from the Central region of human CTSK.
Host Species: Rabbit
Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Physical State: Liquid
CAS NO.: 451462-58-1
Product: H-1152
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 2 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Cathepsin K, Cathepsin O, Cathepsin O2, Cathepsin X, CTSK, CTSO, CTSO2
Accession NO.: P43235
Protein Ino: 1168793
Official Symbol: CTSK
Geneid: 1513
Background: The protein encoded by this gene is a lysosomal cysteineproteinase involved in bone remodeling and resorption. Thisprotein, which is a member of the peptidase C1 protein family, ispredominantly expressed in osteoclasts. However, the encodedprotein is also expressed in a significant fraction of human breastcancers, where it could contribute to tumor invasiveness. Mutationsin this gene are the cause of pycnodysostosis, an autosomalrecessive disease characterized by osteosclerosis and shortstature. This gene may be subject to RNA editing. [provided byRefSeq].
PubMed ID:http://aac.asm.org/content/37/7/1518.abstract
