Product Name: CTRP6 Antibody [256-E]
Species Reactivity: Human
Tested Applications: ELISA, WB
Applications: ELISA: (direct or indirect: 1:200-1:500). Immunohistochemistry (paraffin sections): 1:200. Western blot: (1:200-1:500 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature). Optimal conditions should be determined individually for each application.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Recombinant human CTRP6 (globular domain-less).
Host Species: Mouse
Purification:
Physical State: Liquid
CAS NO.: 60142-96-3
Product: Gabapentin
Buffer: Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration: 0.5 mg/ml
Storage Conditions: Stable for at least 1 year after receipt when stored at -20˚C.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: Complement C1q Tumor Necrosis Factor-related Protein 6; C1QTNF6; C1qTNF-related Protein 6; ZACRP 6
Accession NO.: AAQ88740
Protein Ino: 37181873
Official Symbol: C1QTNF6
Geneid: 114904
Background: CTRP6 mediates the phosphorylation of AMPK and acetyl-CoA carboxylase (ACC) in skeletal muscle cells, subsequently mediating glycogen accumulation and fatty acid oxidation. It induces the expression of the potent anti-inflammatory cytokine IL-10 in macrophages. CTRP6 may be a potential serum marker for hepatocellular carcinoma, contributing to tumor angiogenesis by activating the Akt pathway. CTRP6 was also shown to be associated with obesity, type 1 diabetes mellitus (T1D), vitiligo (depigmentation of the skin) and ASFV (African Swine Fever Virus). CTRP6 forms homotrimers and higher-order oligomers and it may also form heteromeric complexes with CTRP1. May be involved in kidney inflammation.
PubMed ID:http://aac.asm.org/content/37/7/1468.abstract
