Product Name: CRYM Antibody
Species Reactivity: Mouse
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 34 kDa
Immunogen: This CRYM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the Central region of human CRYM.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 4311-88-0
Product: Necrostatin-1
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.35 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Ketimine reductase mu-crystallin, NADP-regulated thyroid-hormone-binding protein, CRYM, THBP
Accession NO.: Q14894
Protein Ino: 2498259
Official Symbol: CRYM
Geneid: 1428
Background: Crystallins are separated into two classes: taxon-specificand ubiquitous. The former class is also calledphylogenetically-restricted crystallins. The latter classconstitutes the major proteins of vertebrate eye lens and maintainsthe transparency and refractive index of the lens. This geneencodes a taxon-specific crystallin protein that binds NADPH andhas sequence similarity to bacterial ornithine cyclodeaminases. Theencoded protein does not perform a structural role in lens tissue,and instead it binds thyroid hormone for possible regulatory ordevelopmental roles. Mutations in this gene have been associatedwith autosomal dominant non-syndromic deafness. Multiplealternatively spliced transcript variants have been found for thisgene.
PubMed ID:http://aac.asm.org/content/37/4/839.abstract
