Product Name: CRX Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 32 kDa
Immunogen: This CRX antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 294-297 amino acids from the C-terminal region of human CRX.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 1345675-02-6
Product: ETP-46464
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Cone-rod homeobox protein, CRX, CORD2
Accession NO.: O43186
Protein Ino:
Official Symbol: CRX
Geneid: 1406
Background: Binds and transactivates the sequence 5-TAATC[CA]-3 which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, e.g. NRL and RX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors.
PubMed ID:http://aac.asm.org/content/37/4/741.abstract
