Product Name: CRIM1 Antibody
Species Reactivity: Human
Tested Applications: ELISA, IF, WB
Applications: CRIM1 antibody can be used for detection of Crim1 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: CRIM1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human Crim1.The immunogen is located within amino acids 910 – 960 of CRIM1.
Host Species: Rabbit
Purification: CRIM1 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 103639-04-9
Product: Ondansetron (hydrochloride dihydrate)
Buffer: CRIM1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: CRIM1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CRIM1 Antibody: S52, CRIM-1, S52, UNQ1886/PRO4330, Cysteine-rich motor neuron 1 protein, Cysteine-rich repeat-containing protein S52
Accession NO.: NP_057525
Protein Ino: 10092639
Official Symbol: CRIM1
Geneid: 51232
Background: CRIM1 Antibody: CRIM1 (cysteine-rich motor neuron 1), a glycosylated type I transmembrane protein, plays a role in tissue development i.e. capillary formation and maintenance during angiogenesis. It contains an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 interacts with BMP4 and BMP7 via the CRRs and functions as an antagonist. CRIM1 is developmentally expressed in a number of tissues including the pancreas, kidney, placenta, brain and blood vessels. CRIM1 may participate in CNS and placental development by interacting with growth factors involved in motor neuron differentiation and survival.
PubMed ID:http://aac.asm.org/content/37/3/559.abstract
