Product Name: CRB1 Antibody
Species Reactivity: Human
Tested Applications: ELISA, WB
Applications: CRB1 antibody can be used for detection of CRB1 by Western blot at 1 – 2 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 142 kDa
Immunogen: Rabbit polyclonal CRB1 antibody was raised against an 18 amino acid peptide near the center of human CRB1.The immunogen is located within amino acids 780 – 830 of CRB1.
Host Species: Rabbit
Purification: CRB1 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 775351-65-0
Product: Imeglimin
Buffer: CRB1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: CRB1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CRB1 Antibody: LCA8, RP12, Protein crumbs homolog 1
Accession NO.: NP_001180569
Protein Ino: 302370926
Official Symbol: CRB1
Geneid: 23418
Background: CRB1 Antibody: CRB1 (Crumbs homolog 1) plays a role in photoreceptor morphogenesis in the retina. It may maintain cell polarization and adhesion. CRB1 is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. The first identified human homolog, CRB1, is expressed in retina and some parts of the brain, leaving room for another homolog to function in epithelial tissues. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis.
PubMed ID:http://aac.asm.org/content/37/2/347.abstract
