Product Name: CPSF3L Antibody
Species Reactivity: Human
Tested Applications: IF, IHC-P, WB
Applications: For WB starting dilution is: 1:1000For IHC-P starting dilution is: 1:10~50For IF starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 68 kDa
Immunogen: This CPSF3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 amino acids from the N-terminal region of human CPSF3L.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 639052-78-1
Product: LH846
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Integrator complex subunit 11, Int11, 3127-, Cleavage and polyadenylation-specific factor 3-like protein, CPSF3-like protein, Protein related to CPSF subunits of 68 kDa, RC-68, CPSF3L, INTS11, RC68
Accession NO.: Q5TA45
Protein Ino: 118572557
Official Symbol: CPSF3L
Geneid: 54973
Background: The Integrator complex contains at least 12 subunits andassociates with the C-terminal domain of RNA polymerase II largesubunit (POLR2A; MIM 180660) and mediates the 3-prime endprocessing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2(RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit ofthe Integrator complex (Baillat et al., 2005 [PubMed16239144]).
PubMed ID:http://aac.asm.org/content/37/2/203.abstract
