Product Name: COX18 Antibody
Species Reactivity: Human
Tested Applications: ELISA, WB
Applications: COX18 antibody can be used for detection of COX18 by ELISA at 1:1562500. COX18 antibody can be used for detection of COX18 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 37 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COX18.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 166663-25-8
Product: Anidulafungin
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store COX18 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: COX18, COX18HS, FLJ38991, MGC126733
Accession NO.: NP_776188
Protein Ino: 28395049
Official Symbol: COX18
Geneid: 285521
Background: COX18 is required for the insertion of integral membrane proteins into the mitochondrial inner membrane. COX18 is essential for the activity and assembly of cytochrome c oxidase. COX18 plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2; MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 [PubMed 16212937]).
PubMed ID:http://aac.asm.org/content/36/12/2808.abstract
