Product Name: COPS5 Antibody [2A10.8]
Species Reactivity: Human, Mouse
Tested Applications: IF, IHC, IP, WB
Applications: COPS5 antibody can be used in Western Blot starting at 1 – 2 μg/mL, and immunohistochemistry starting at 10 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: COPS5 monoclonal antibody was raised against a peptide located in the full – length mouse E. coli expressedCOPS5 (Mouse).
Host Species: Mouse
Purification: Protein G Column
Physical State: Liquid
CAS NO.: 120279-96-1
Product: Dorzolamide
Buffer: PBS, pH 7.4
Concentration: 1 mg/ml
Storage Conditions: Antibody should be stored long term (months) at -20 ˚C and short term (weeks) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: COPS5, 38 kDa Mov34 homolog, JAB1, Signalosome subunit 5, MOV-34, SGN5, CSN5
Accession NO.: Q92905
Protein Ino: 55976562
Official Symbol: COPS5
Geneid: 10987
Background: JAB-1 is a 38 kDa protein which was originally described as a coactivator for cJUN. It is present in a large protein complex called the Signalosome, which has been proposed to play a signaling role in mammalian cells. This protein complex appears to be analogous to the COP9 complex in plants, which is important in light-mediated plant development. Although the specific function of JAB-1 in this complex is unclear, it has recently been implicated in targeting proteins for degradation by the proteasome.
PubMed ID:http://aac.asm.org/content/36/12/2611.abstract
