Product Name: COL6A1 Antibody
Species Reactivity: Bovine, Human
Tested Applications: ELISA, IF, IHC, IP, WB
Applications: COL6A1 antibody can be used in immunohistochemistry starting at 1.25 – 2.5 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: COL6A1 antibody was raised against Collagen Type VI from human and bovine placenta (Human).
Host Species: Rabbit
Purification: Immunoaffinity Chromatography
Physical State: Liquid
CAS NO.: 137862-53-4
Product: Valsartan
Buffer: 0.125 M sodium borate, 0.075 M sodium chloride, 0.005 M EDTA;, pH 8.0, 0.01% sodium azide.
Concentration:
Storage Conditions: Store COL6A1 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: OPLL
Accession NO.: P12109
Protein Ino: 125987811
Official Symbol: COL6A1
Geneid: 1291
Background: Collagens are highly conserved throughout evolution and are characterized by an uninterrupted Glycine-X-Y triplet repeat that is a necessary part of the triple helical structure. For these reasons it is often extremely difficult to generate antibodies with specificities to collagens. The development of type specific antibodies is dependent on NON-DENATURED three-dimensional epitopes. Collagens are extensively purified for immunization from human and bovine placenta and cartilage by limited pepsin digestion and selective salt precipitation. This preparation results in a native conformation of the protein. Antibodies are isolated from rabbit antiserum and are extensively cross-adsorbed by immunoaffinity purification to produce type specific antibodies. Greatly diminished reactivity and selectivity of these antibodies will result if denaturing and reducing conditions of SDS-PAGE and immunoblotting are used.
PubMed ID:http://aac.asm.org/content/36/10/2316.abstract
