Product Name: CLEC1 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: Western blot: 2-5 ug/mlProvided assay concentrations are suggestions only, CLEC1 antibody titration may be required for optimal results.
User Note: Optimal dilutions for each application to be determined by the researcher
Predicted Molecular Weight:
Immunogen: A recombinant protein fragment from the N-terminal portin of human CLEC1 was used as the immunogen for this antibody.
Host Species: Rabbit
Purification: Protein A purified antibody
Physical State: Liquid
CAS NO.: 645-05-6
Product: Altretamine
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.5 mg/mL
Storage Conditions: Aliquot and Store at -20C. Avoid freez-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names:
Accession NO.:
Protein Ino:
Official Symbol: CLEC1A
Geneid: 51267
Background: CLEC1 is a C-type lectin receptor and part of the ‘Dectin-1 cluster’ subfamily which also includes Dectin-1, LOX-1, CLEC-2, MICL, CLEC12B, and CLEC9A. Similar to other family members, CLEC1 displays N-liked glycosylation and dimerization characteristics, and is found on dendritic cells, monocytes and granulocytes. However, unlike other family members, CLEC1 expression level is upregulated by IL-10 and TGFb, but not by pro-inflammatory stimuli, and it is expressed on endothelial cells. Enhanced expression at allograft sites suggests CLEC1 may have an immune-regulatory function and may support allograft tolerance.
PubMed ID:http://aac.asm.org/content/36/6/1192.abstract
