Product Name: CLDN6 Antibody
Species Reactivity: Human, Mouse
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 23 kDa
Immunogen: This CLDN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-159 amino acids from the Central region of human CLDN6.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 122841-10-5
Product: Cefoselis
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Claudin-6, Skullin, CLDN6
Accession NO.: P56747
Protein Ino: 90183180
Official Symbol: CLDN6
Geneid: 9074
Background: Tight junctions represent one mode of cell-to-celladhesion in epithelial or endothelial cell sheets, formingcontinuous seals around cells and serving as a physical barrier toprevent solutes and water from passing freely through theparacellular space. These junctions are comprised of sets ofcontinuous networking strands in the outwardly facing cytoplasmicleaflet, with complementary grooves in the inwardly facingextracytoplasmic leaflet. This gene encodes a component of tightjunction strands, which is a member of the claudin family. Theprotein is an integral membrane protein and is one of the entrycofactors for hepatitis C virus. The gene methylation may beinvolved in esophageal tumorigenesis. This gene is adjacent toanother family member CLDN9 on chromosome 16.
PubMed ID:http://aac.asm.org/content/36/5/1155.abstract
