Product Name: CLDN1 Antibody
Species Reactivity: Dog, Human
Tested Applications: ELISA, IHC, WB
Applications: CLDN1 antibody can be used for detection of CLDN1 by ELISA at 1:312500. CLDN1 antibody can be used for detection of CLDN1 by western blot at 1.0-5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 23 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLDN1.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 1333207-63-8
Product: SAR7334 (hydrochloride)
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store CLDN1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CLDN1, CLD1, SEMP1, ILVASC
Accession NO.: NP_066924
Protein Ino: 10863887
Official Symbol: CLDN1
Geneid: 9076
Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This protein, a member of the claudin family, is an integral membrane protein and a component of tight junction strands.
PubMed ID:http://aac.asm.org/content/36/5/1068.abstract
