Product Name: CK-1alpha (phospho Tyr294) Antibody
Species Reactivity: Mouse, Rat
Tested Applications: IHC
Applications: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
User Note:
Predicted Molecular Weight: 37 kDa
Immunogen: CK-1alpha (phospho Tyr294) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 294 (Y-D-Y (p)-T-F) derived from Human CK-1alpha.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Physical State: Liquid
CAS NO.: 1197196-48-7
Product: UNC0224
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: KC1A, CKI-alpha, CSNK1A1, alpha isoform, Casein kinase I
Accession NO.: NP_001883.4
Protein Ino: 68303575
Official Symbol: CSNK1A1, CSNK1A1L
Geneid: 1452/122011
Background: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at Ser-45. May play a role in segregating chromosomes during mitosis.
PubMed ID:http://aac.asm.org/content/36/4/796.abstract