Product Name: CKR2 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: MCP-1 receptor antibody can be used for the detection of MCP-1 receptor by Western Blot.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 16.3 kDa (calculated)
Immunogen: 16438
Host Species: Chicken
Purification: Immunoaffinity Purified
Physical State: Liquid
CAS NO.: 6384-92-5
Product: NMDA
Buffer: Phosphate-Buffered Saline. No preservatives added.
Concentration: 1 mg/mL
Storage Conditions: CKR2 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CMKBR2, C-C chemokine receptor type 2, Monocyte chemoattractant protein 1 receptor, C-C CKR-2, MCP1 receptor
Accession NO.: NP_000638.1
Protein Ino: 4502633
Official Symbol: CCR2
Geneid: 729230
Background: This protein is two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene
PubMed ID:http://aac.asm.org/content/36/4/873.abstract
