Product Name: CFTR Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IF, IHC-P, WB
Applications: CFTR antibody can be used for detection of CFTR by Western blot at 1 – 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 163 kDa Observed: 160 kDa
Immunogen: CFTR antibody was raised against an 18 amino acid peptide near the carboxy terminus of human CFTR.The immunogen is located within amino acids 1290 – 1340 of CFTR.
Host Species: Rabbit
Purification: CFTR antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 155-41-9
Product: Methscopolamine (bromide)
Buffer: CFTR Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: CFTR antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CFTR Antibody: CF, MRP7, ABC35, ABCC7, CFTR/MRP, TNR-CFTR, dJ760C5.1, Cystic fibrosis transmembrane conductance regulator, ATP-binding cassette sub-family C member 7, CFTR
Accession NO.: NP_000483
Protein Ino: 90421313
Official Symbol: CFTR
Geneid: 1080
Background: The cystic fibrosis transmembrane conductance regulator (CFTR) protein is a member of the ATP-binding cassette (ABC) transporter superfamily, and a member of the MRP subfamily that is involved in multi-drug resistance (1,2). CFTR functions as a chloride channel and controls the regulation of other transport pathways (3). Mutations in this gene are associated with the autosomal recessive disorder cystic fibrosis, the most common, fatal, inherited disease of caucasian populations (1).
PubMed ID:http://aac.asm.org/content/35/12/2473.abstract
