Product Name: CENPP Antibody
Species Reactivity: Human
Tested Applications: ELISA, WB
Applications: CENPP antibody can be used for detection of CENPP by ELISA at 1:312500. CENPP antibody can be used for detection of CENPP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 33 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CENPP.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 39133-31-8
Product: Trimebutine
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store CENPP antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CENPP, CENP-P, FLJ33928, RP11-19J3.3
Accession NO.: NP_001012267
Protein Ino: 59709758
Official Symbol: CENPP
Geneid: 401541
Background: CENPP is the component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. CENPP may be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.CENPP is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).
PubMed ID:http://aac.asm.org/content/35/11/2246.abstract
