Product Name: CD10 Antibody [2A1H5E1]
Species Reactivity: Human
Tested Applications: ELISA, IHC
Applications: IHC(P):Dilution 1:100 – 1:200IHC(F):Dilution 1:200 – 1:400ELISA:Propose dilution 1:10,000.Determining optimal working dilutions by titration test.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Ni-NTA purified recombinant human CD-10 expressed in E. Coli strain BL21 (DE3).
Host Species: Mouse
Purification: Antibody is purified by protein G affinity chromatography.
Physical State:
CAS NO.: 1627503-67-6
Product: LDN-214117
Buffer: Purified antibody in PBS containing 0.03% sodium azide
Concentration:
Storage Conditions: CD10 monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: EPN, Atriopeptidase, CALLA, NEP, SFE, CD10
Accession NO.: P08473
Protein Ino: 128062
Official Symbol: MME
Geneid: 4311
Background: CD10 is a 100 kDa glycoprotein, also designated Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt’s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.
PubMed ID:http://aac.asm.org/content/43/10/2417.abstract
