Product Name: CCL27 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 13 kDa
Immunogen: This CCL27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-102 amino acids from the C-terminal region of human CCL27.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 380607-77-2
Product: CMPDA
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: C-C motif chemokine 27, CC chemokine ILC, Cutaneous T-cell-attracting chemokine, CTACK, ESkine, IL-11 R-alpha-locus chemokine, Skinkine, Small-inducible cytokine A27, CCL27, ILC, SCYA27
Accession NO.: Q9Y4X3
Protein Ino: 7674366
Official Symbol: CCL27
Geneid: 10850
Background: This gene is one of several CC cytokine genes clustered onthe p-arm of chromosome 9. Cytokines are a family of secretedproteins involved in immunoregulatory and inflammatory processes.The CC cytokines are proteins characterized by two adjacentcysteines. The protein encoded by this gene is chemotactic forskin-associated memory T lymphocytes. This cytokine may also play arole in mediating homing of lymphocytes to cutaneous sites. Itspecifically binds to chemokine receptor 10 (CCR10). Studies of asimilar murine protein indicate that these protein-receptorinteractions have a pivotal role in T cell-mediated skininflammation.
PubMed ID:http://aac.asm.org/content/43/9/2121.abstract